These are obviously preliminary results, but how many of the Leopard Pi Symbol National Pi Day Gifts Shirt here dismissing them out of hand is also the kind of people who say “trust the science” when the science agrees with them? This is a big problem even for scientifically literate people. Everyone wants their own ideology confirmed. Way too many people are going to read this and decide either “the science is out and microdosing is useless for these conditions” or “these researchers are obviously biased against the truth and the small sample size/limited scope Leopard Pi Symbol National Pi Day Gifts Shirt it”. The reality is of course neither. This small study supports a hypothesis, but the larger collection of research on this subject is still in its infancy. It takes a conscious effort to drop our beliefs at the door and take good science for exactly what it is. That’s why we do meta-analyses once numerous studies are published on a topic. Then we can see the composite of all the data on the topic and see how heavily the existing research favors a particular answer. We should be studying the efficacy of normal dosing before we even begin to talk about microdosing. The focus on that is the ideology of trying to find a benefit of the drug without experiencing the drug which is what the drug is an experience that your brain uses to change itself at an accelerated rate.
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I read an article some years ago on increased expression of BDNF following Leopard Pi Symbol National Pi Day Gifts Shirt of a couple of different psychedelic substances including psilocybin and LSD, and they found the effect on BDNF expression bei g raised for months after the experience was actually stronger with microdosing. Now obviously there are more effects to the drugs than that, and the 5HT2A interplay in ferrying information to and from the frontal lobe does seem to be central to the hallucinogenic effects of these drugs and may play a serious role in their therapeutic potential, so I suspect you’re right. But there are interesting dynamics at play with micro-dosing and Brain-Derived Neurotrophic Factor at least, a brain growth protein that has been identified as a therapeutic target for depression. I’ve always wondered with all the anecdotal reports on microdosing efficacy, I wonder if microdosing has more potential Retro Vintage Pi Day 3.14 Funny Math Nerd Shirt if you’ve experienced a larger dose of the same molecule before, have the priming so to speak. This study wouldn’t be looking at things like that, in fact, admitting to the use of the drug in question would classically disqualify someone as a research subject. So that might explain some discrepancy between these studies findings and the flood of anecdotal reports extolling the virtues of microdosing, as people in the wild so to speak who are micro-dosing are far more likely to have taken a full dose, while people in a study on micro-dosing are far less likely.
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